ADC Conjugation Services
You provide the antibody and linker-payload — we handle the conjugation chemistry and deliver a characterized, ready-to-use conjugate. We support every major conjugation chemistry and format with integrated access to trusted partners for antibody, linker, and payload synthesis.
Conjugate Types We Produce
We work with a wide range of antibody formats and payload classes. You supply the components; we perform the conjugation and deliver the finished conjugate.
Antibody-Drug Conjugates (ADC)
- IgG1, IgG2, IgG4 formats
- Bispecific antibodies (BsAb)
- Dual-payload ADCs
- Single-chain variable fragment (scFv) conjugates
- Isotype control ADC generation
Next-Generation Conjugate Formats
- Degrader-Antibody Conjugates (DAC) — PROTAC/molecular glue payloads
- Antibody-Oligonucleotide Conjugates (AOC) — siRNA, ASO, mRNA
- Custom bioconjugate formats on request
- Multifunctional conjugation platforms
Research & Tool Conjugates
- Antibody–fluorophore conjugates (flow cytometry, imaging)
- Enzyme conjugates (HRP, AP)
- Biotinylated antibodies
- Custom labeling for assay development
Conjugation Chemistry Options
We offer both traditional stochastic and precision site-specific conjugation strategies, selected based on your DAR requirements, payload chemistry, and development stage.
Stochastic Conjugation
- Native cysteine (interchain disulfide reduction)
- Native lysine (NHS ester chemistry)
- Broad DAR distribution (DAR 2–8)
- Cost-effective for early-stage screening
- Rapid turnaround for POC studies
Site-Specific Conjugation
- Engineered cysteine (THIOMAB) — homogeneous DAR 2
- Glycan conjugation (oxidized sugar attachment)
- ‘Click’ chemistry (DBCO/azide, TCO/tetrazine)
- Unnatural amino acid incorporation
- Improved PK/PD and therapeutic index vs. stochastic
Linker-Payload Optimization
Not sure which of your linker-payload options is best suited to your target? Our team can help you design a screening panel and use our HTP platform to conjugate and test multiple combinations in parallel — dramatically reducing the time to identify your lead ADC. You provide the antibody and the linker-payload candidates; we run the conjugations and characterization.
What We Need From You
You Provide
- → Your antibody (we can advise on format and quantity needed)
- → Your linker-payload (client-supplied; synthesis available through trusted partners)
- → Your target DAR and scale requirements
We Deliver
- → Purified, characterized conjugate at your requested scale
- → DAR, purity, and yield data
- → Full data report and recommendations for next steps
