iQ Biosciences offers the following Immuno-Oncology Bioservices:
Immune Checkpoint Binding and Interaction Assays
iQ’s immune checkpoint inhibitor binding assay is a reliable method to screen potential candidates that interfere with the binding between immune checkpoint proteins and their ligands. We have developed a flow cytometry-based assay to demonstrate therapeutic molecule-mediated blocking of immune checkpoint protein with its cognate ligand.
Immune Checkpoint Functional Assay
Immune checkpoint inhibitor functional assays are important in demonstrating restoration of immune function in the presence of therapeutic candidates. Our expertise in performing immune checkpoint inhibitor functional assays allow us to determine if your molecule of interest can restore immune function. We can assay for function using various readouts, such as proliferation and/or cytokine production, in cell line or primary cell systems.