Hemolysis Assay
The expert immunologists at iQ Biosciences perform in vitro Hemolysis Assays to assess red blood cell lysis following exposure to small molecules, biologics and excipients. Using hemoglobin release as a marker, we evaluate hemolytic potential to identify safety risks, supporting FDA-recommended preclinical assessments with high-quality data for regulatory submissions and therapeutic development.
Our services
- Evaluate your small molecule, biologic, or formulation excipients for its potential to lyse red blood cells
- Receive a personalized experimental design to ensure the most relevant data is obtained with the options to examine all relevant in vivo pharmacologically relevant blood from appropriate species
- Whole blood procured from local IRB-approved blood centers and used within four (4) hours of collection
- All assays are performed with high-quality reagents and strict controls by experienced immunologists
The iQ Experience
Tailored Experiments
Your research is important to us. Our scientists will work through each step of the process with you, including assay design, data analysis, and recommendations for future studies.
Streamlined Process
Simplify your workflow. Bypass the middle-man: at iQ Biosciences, you’ll get immediate access to our biospecimen inventory, saving you both valuable time and money.
Expertise
We’re experts – so you don’t have to be. Augmenting years of experience in immunology and working with immune assays, our scientists stay current with the latest publications and technology.
Exceptional Service
We’re here to help. We know the challenges you’re facing: whether it be through expedited service or our complimentary consulting services, our team is dedicated to helping you reach your goals.
Service Overview
How can iQ Biosciences help achieve your goals the smarter way?
We measure in vitro hemolysis by evaluating hemoglobin release as a marker of red blood cell lysis following test agent exposure. Exposure to drugs (biologics or excipients) can cause hemolysis, even in normal adults, potentially resulting in neutropenia, thrombocytopenia, hemolytic anemia, aplastic anemia, and macrocytic anemia. Therefore, according to FDA recommendations, testing for hemolytic potential should be performed.
Figure 1: Hemolysis Assay
Order Information
Pricing
At iQ Biosciences, we understand that each client is unique. Upon quote request, we will provide complimentary consulting services to determine how to tailor our services to best meet your goals. Based on this preliminary assessment, we will be able to provide a price quote.
Expected Timetable
Fit a timetable appropriate to your research goals. We work with you to determine your expected turn-around on a case-by-case basis and ensure that our services fit your needs. Some experiments may require an expedited service – please inquire for more information.
