- High-quality cynomolgus monkey splenocytes sourced responsibly from a vetted third-party facility
- High viability (typically > 70%) after thawing
- Used for a wide variety of safety assessment and functional assays
- All orders come with an iQ Certificate of Analysis
- Normally ships out same business day
Cynomolgus Monkey Splenocytes
$350.00 – $500.00
- Additional information
- Donor Request
- iQ Experience
- Shipping Information
About the Cynomolgus Monkey (or Cynomolgus Macaque)
Cynomolgus macaques are the most commonly utilized non-human primates in biomedical research. They are employed in numerous research areas, such as immunology, neuroscience, oncology, diabetes, and pharmacology due to their physiology.
Application Summary for Cynomolgus Monkey Splenocytes
Cynomolgus monkey splenocytes (or cyno monkey splenocytes) can be used for a wide variety of safety assessment and functional studies. They are commonly employed in pre-clinical settings to ensure biologics are not eliciting unwanted functions, such as cytokine release and toxicity. They are also used in many immunology-based applications, such as ELISPOT, cytokine production assays, and cytotoxicity assays to measure ADCC or CDC in response to biologics. Cynomolgus monkey splenocytes can also be used in ex-vivo applications for cell population characterization. They can also be used to test the toxicity of compounds.
Isolation of Cynomolgus Monkey Splenocytes
Spleens from cynomolgus monkeys are collected responsibly at third party facilities. These facilities are vetted to ensure they operate according to local regulations and laws. Since the facility is local, the tissue is quickly transported to iQ’s facility for processing.
At our facility, the splenic tissue is carefully dissociated through a gentle mechanical process to generate a single cell suspension under sterile conditions. The suspension is then carefully passed through a filter to remove any fat and/or connective tissue and subsequently depleted of red blood cells in a manner that is not damaging to the other cells. The purified splenocytes are then frozen based on iQ Biosciences’ quality-controlled cryopreservation protocol to promote recoverability and viability once in the end user’s hands.
Cryopreservation and Storage
Our cyno splenocytes are cryopreserved carefully using iQ Biosciences’ cryopreservation protocol that ensures high viability (typically > 70%) after thawing.
Cells should be stored at < -120°C once they are received, such as within a liquid nitrogen tank (vapor phase).
Typically > 70%
We are happy to accommodate the following donor requests if inventory is available. Feel free to inquire prior to ordering, or specify your interest in the "Order notes" section during checkout and we will follow-up with your shortly after your order is processed:
- Single or multiple donors for a particular product (SKU). Indicate number of vials from each individual donor
- Donor-matched PBMCs
- Donor(s) with a higher percentage of the cells of interest, i.e., B cells, CD14+ cells, CD4+ cells, CD8+ cells, or NK cells (for PBMC products only)
We are Committed to Ethical Practices
iQ Biosciences’ primary cell products from non-human primates are collected under approved IACUC protocol, which was developed in consultation with the Attending Veterinarian and is consistent with current veterinary standards. The collection facility is AAALACi and PHS accredited, and all animal housing, handling, and research protocols are consistent with standards set forth by the Animal Welfare Act, NIH's Policy on Humane Care and Use of Animals and the Guide for the Care and Use of Animals. All animal housing and handling is done in such a way to minimize stress and risk of injury to the animal.
For US customers, we ship via FedEx Overnight Shipping. Shipping charges will vary per shipping address (based on ZIP code) and are estimated to be $110.
For international (non-US) customers, we work closely with you and our couriers to ensure all necessary documentation is in place for international shipments to significantly reduce the chance of delays at Customs. For the export of non-human primate samples, this includes preparing CITES permits, as well as any other documentation as required by country. Please submit an inquiry to firstname.lastname@example.org for your estimated time of delivery and shipping charges.